Integration of ß-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity.

Parker, J Alex; Vazquez-Manrique, Rafael P; Tourette, Cendrine; Farina, Francesca; Offner, Nicolas; Mukhopadhyay, Arnab; Orfila, Anne-Marie; Darbois, Aurélie; Menet, Sophie; Tissenbaum, Heidi A; Neri, Christian

Parker, J Alex; Vazquez-Manrique, Rafael P; Tourette, Cendrine; Farina, Francesca; Offner, Nicolas; Mukhopadhyay, Arnab; Orfila, Anne-Marie; Darbois, Aurélie; Menet, Sophie; Tissenbaum, Heidi A; Neri, Christian.

Affiliation

Parker JA; INSERM, Unit 894, Laboratory of Neuronal Cell Biology and Pathology, 75014 Paris, France.

J Neurosci ; 32(36): 12630-40, 2012 Sep 05.

Article in En | MEDLINE | ID: mdl-22956852

Subject(s)

Caenorhabditis elegans Proteins/biosynthesis; Caenorhabditis elegans Proteins/physiology; Cytoskeletal Proteins/biosynthesis; Nerve Tissue Proteins/toxicity; Signal Transduction/physiology; Sirtuins/physiology; Transcription Factors/biosynthesis; beta Catenin/biosynthesis; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins/genetics; Cell Survival/drug effects; Cell Survival/physiology; Cytoskeletal Proteins/genetics; Forkhead Transcription Factors; Huntingtin Protein; Nerve Tissue Proteins/antagonists & inhibitors; Nerve Tissue Proteins/genetics; Sirtuins/genetics; Transcription Factors/genetics; beta Catenin/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Signal Transduction / Cytoskeletal Proteins / Caenorhabditis elegans Proteins / Sirtuins / Beta Catenin / Nerve Tissue Proteins Limits: Animals Language: En Journal: J Neurosci Year: 2012 Type: Article Affiliation country: France

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