Inhibition potential of glimepiride (gli) towards important UDP-glucuronosyltransferase (UGT) isoforms in human liver.

Fu, Jian-Fang; Ren, Qin-You; Zhang, Nan-Yan; Gao, Bin; Tu, Yan-Yang; Fu, Guo-Qiang; Li, Dao-Hai; Zhang, Yong-Sheng

Fu, Jian-Fang; Ren, Qin-You; Zhang, Nan-Yan; Gao, Bin; Tu, Yan-Yang; Fu, Guo-Qiang; Li, Dao-Hai; Zhang, Yong-Sheng.

Affiliation

Fu JF; Endocrinology Department, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi, China.

Pharmazie ; 67(8): 715-7, 2012 Aug.

Article in En | MEDLINE | ID: mdl-22957438

Subject(s)

Glucuronosyltransferase/antagonists & inhibitors; Hypoglycemic Agents/pharmacology; Liver/enzymology; Sulfonylurea Compounds/pharmacology; Humans; Hymecromone/analogs & derivatives; Hymecromone/metabolism; Isoenzymes/antagonists & inhibitors; Kinetics; Liver/drug effects; Substrate Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Sulfonylurea Compounds / Glucuronosyltransferase / Hypoglycemic Agents / Liver Limits: Humans Language: En Journal: Pharmazie Journal subject: FARMACIA Year: 2012 Type: Article Affiliation country: China

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