Dectin-1 and IL-17A suppress murine asthma induced by Aspergillus versicolor but not Cladosporium cladosporioides due to differences in ß-glucan surface exposure.

Mintz-Cole, Rachael A; Gibson, Aaron M; Bass, Stacey A; Budelsky, Alison L; Reponen, Tiina; Hershey, Gurjit K Khurana

Mintz-Cole, Rachael A; Gibson, Aaron M; Bass, Stacey A; Budelsky, Alison L; Reponen, Tiina; Hershey, Gurjit K Khurana.

Affiliation

Mintz-Cole RA; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

J Immunol ; 189(7): 3609-17, 2012 Oct 01.

Article in En | MEDLINE | ID: mdl-22962686

Subject(s)

Anti-Asthmatic Agents/administration & dosage; Aspergillus/immunology; Asthma/immunology; Asthma/pathology; Cladosporium/immunology; Interleukin-17/administration & dosage; Lectins, C-Type/administration & dosage; beta-Glucans/administration & dosage; Animals; Anti-Asthmatic Agents/metabolism; Aspergillus/metabolism; Asthma/prevention & control; Bronchial Hyperreactivity/immunology; Bronchial Hyperreactivity/pathology; Bronchial Hyperreactivity/prevention & control; Cladosporium/metabolism; Eosinophils/immunology; Eosinophils/pathology; Immunophenotyping; Inflammation Mediators/administration & dosage; Lectins, C-Type/deficiency; Lectins, C-Type/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils/immunology; Neutrophils/pathology; Spores, Fungal/immunology; Spores, Fungal/metabolism; Surface Properties; beta-Glucans/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aspergillus / Asthma / Cladosporium / Anti-Asthmatic Agents / Interleukin-17 / Lectins, C-Type / Beta-Glucans Limits: Animals Language: En Journal: J Immunol Year: 2012 Type: Article Affiliation country: United States

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