Autophagy regulates TNF&#945;-mediated joint destruction in experimental arthritis.

Lin, Neng-Yu; Beyer, Christian; Giessl, Andreas; Kireva, Trayana; Scholtysek, Carina; Uderhardt, Stefan; Munoz, Luis Enrique; Dees, Clara; Distler, Alfiya; Wirtz, Stefan; Krönke, Gerhard; Spencer, Brian; Distler, Oliver; Schett, Georg; Distler, Jörg H W

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.

Lin, Neng-Yu; Beyer, Christian; Giessl, Andreas; Kireva, Trayana; Scholtysek, Carina; Uderhardt, Stefan; Munoz, Luis Enrique; Dees, Clara; Distler, Alfiya; Wirtz, Stefan; Krönke, Gerhard; Spencer, Brian; Distler, Oliver; Schett, Georg; Distler, Jörg H W.

Affiliation

Lin NY; Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.

Ann Rheum Dis ; 72(5): 761-8, 2013 May.

Article in En | MEDLINE | ID: mdl-22975756

Subject(s)

Arthritis, Experimental/immunology; Arthritis, Experimental/pathology; Autophagy/immunology; Joints/pathology; Tumor Necrosis Factor-alpha/immunology; Adoptive Transfer; Animals; Apoptosis Regulatory Proteins/genetics; Autophagy-Related Protein 7; Beclin-1; Biomarkers; Bone Marrow Transplantation; Bone Resorption/immunology; Bone Resorption/pathology; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Microtubule-Associated Proteins/genetics; Osteoclasts/immunology; Osteoclasts/pathology; Osteoclasts/ultrastructure; Tumor Necrosis Factor-alpha/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Experimental / Autophagy / Tumor Necrosis Factor-alpha / Joints Type of study: Prognostic_studies Limits: Animals Language: En Journal: Ann Rheum Dis Year: 2013 Type: Article Affiliation country: Germany

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