Poloxamer-188 attenuates TBI-induced blood-brain barrier damage leading to decreased brain edema and reduced cellular death.

Bao, Hai-Jun; Wang, Tao; Zhang, Ming-Yang; Liu, Ran; Dai, Ding-Kun; Wang, Yao-Qi; Wang, Long; Zhang, Lu; Gao, Yu-Zhen; Qin, Zheng-Hong; Chen, Xi-Ping; Tao, Lu-Yang

Bao, Hai-Jun; Wang, Tao; Zhang, Ming-Yang; Liu, Ran; Dai, Ding-Kun; Wang, Yao-Qi; Wang, Long; Zhang, Lu; Gao, Yu-Zhen; Qin, Zheng-Hong; Chen, Xi-Ping; Tao, Lu-Yang.

Affiliation

Bao HJ; Institute of Forensic Sciences, Soochow University, Suzhou 215123, Jiangsu, China.

Neurochem Res ; 37(12): 2856-67, 2012 Dec.

Article in En | MEDLINE | ID: mdl-23011204

Subject(s)

Blood-Brain Barrier; Brain Edema/prevention & control; Brain Injuries/drug therapy; Cell Death/drug effects; Poloxamer/therapeutic use; Animals; Base Sequence; Blotting, Western; Brain Injuries/physiopathology; DNA Primers; Fluorescent Antibody Technique; Male; Maze Learning; Mice; Poloxamer/pharmacology; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Edema / Brain Injuries / Blood-Brain Barrier / Cell Death / Poloxamer Limits: Animals Language: En Journal: Neurochem Res Year: 2012 Type: Article Affiliation country: China

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