Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms.

Guo, Shangqin; Bai, Haitao; Megyola, Cynthia M; Halene, Stephanie; Krause, Diane S; Scadden, David T; Lu, Jun

Guo, Shangqin; Bai, Haitao; Megyola, Cynthia M; Halene, Stephanie; Krause, Diane S; Scadden, David T; Lu, Jun.

Affiliation

Guo S; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA.

Proc Natl Acad Sci U S A ; 109(41): 16636-41, 2012 Oct 09.

Article in En | MEDLINE | ID: mdl-23012470

Subject(s)

Bone Marrow Neoplasms/genetics; MicroRNAs/genetics; Myeloproliferative Disorders/genetics; Oncogenes/genetics; Animals; Bone Marrow Cells/drug effects; Bone Marrow Cells/metabolism; Bone Marrow Neoplasms/metabolism; Bone Marrow Neoplasms/pathology; Bone Marrow Transplantation; Cell Line; Colony-Forming Units Assay; Doxycycline/pharmacology; Flow Cytometry; Gene Expression Regulation, Neoplastic/drug effects; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology; Interleukin-3/pharmacology; Leukocytes, Mononuclear/drug effects; Leukocytes, Mononuclear/metabolism; Mice; Mice, Inbred C57BL; Myeloproliferative Disorders/metabolism; Myeloproliferative Disorders/pathology; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oncogenes / Bone Marrow Neoplasms / MicroRNAs / Myeloproliferative Disorders Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2012 Type: Article Affiliation country: United States

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