n-3 Long-chain PUFA reduce allergy-related mediator release by human mast cells in vitro via inhibition of reactive oxygen species.

van den Elsen, Lieke W J; Nusse, Yvette; Balvers, Martin; Redegeld, Frank A; Knol, Edward F; Garssen, Johan; Willemsen, Linette E M

van den Elsen, Lieke W J; Nusse, Yvette; Balvers, Martin; Redegeld, Frank A; Knol, Edward F; Garssen, Johan; Willemsen, Linette E M.

Affiliation

van den Elsen LW; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, The Netherlands.

Br J Nutr ; 109(10): 1821-31, 2013 May 28.

Article in En | MEDLINE | ID: mdl-23021516

Subject(s)

Arachidonic Acid/adverse effects; Dietary Fats/therapeutic use; Fatty Acids, Omega-3/therapeutic use; Hypersensitivity/drug therapy; Inflammation/prevention & control; Mast Cells/drug effects; Reactive Oxygen Species/antagonists & inhibitors; Cell Line; Dietary Fats/pharmacology; Docosahexaenoic Acids/pharmacology; Docosahexaenoic Acids/therapeutic use; Eicosapentaenoic Acid/pharmacology; Eicosapentaenoic Acid/therapeutic use; Fatty Acids, Omega-3/pharmacology; Humans; Hypersensitivity/immunology; Hypersensitivity/metabolism; Inflammation/chemically induced; Inflammation/metabolism; Interleukins/metabolism; Mast Cells/metabolism; Mitogen-Activated Protein Kinases/metabolism; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dietary Fats / Fatty Acids, Omega-3 / Arachidonic Acid / Reactive Oxygen Species / Hypersensitivity / Inflammation / Mast Cells Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Br J Nutr Year: 2013 Type: Article Affiliation country: Netherlands

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