Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCÎ³1 and activating NFAT1-dependent RCAN1 expression.

Bala, Kiran; Bosco, Raffaella; Gramolelli, Silvia; Haas, Darya A; Kati, Semra; Pietrek, Marcel; Hävemeier, Anika; Yakushko, Yuri; Singh, Vivek Vikram; Dittrich-Breiholz, Oliver; Kracht, Michael; Schulz, Thomas F

Bala, Kiran; Bosco, Raffaella; Gramolelli, Silvia; Haas, Darya A; Kati, Semra; Pietrek, Marcel; Hävemeier, Anika; Yakushko, Yuri; Singh, Vivek Vikram; Dittrich-Breiholz, Oliver; Kracht, Michael; Schulz, Thomas F.

Affiliation

Bala K; Institute of Virology, Hannover Medical School, Hannover, Germany.

PLoS Pathog ; 8(9): e1002927, 2012 Sep.

Article in En | MEDLINE | ID: mdl-23028325

Subject(s)

Herpesvirus 8, Human/metabolism; Human Umbilical Vein Endothelial Cells/virology; Intracellular Signaling Peptides and Proteins/metabolism; Muscle Proteins/metabolism; Neovascularization, Pathologic/virology; Phospholipase C gamma/metabolism; Viral Proteins/metabolism; Angiogenesis Inducing Agents; Animals; Calcineurin/metabolism; Cell Line; Chlorocebus aethiops; DNA-Binding Proteins; HEK293 Cells; Herpesvirus 8, Human/genetics; Herpesvirus 8, Human/growth & development; Humans; Intracellular Signaling Peptides and Proteins/genetics; Molecular Sequence Data; Muscle Proteins/genetics; NFATC Transcription Factors/metabolism; RNA Interference; RNA, Small Interfering; Sarcoma, Kaposi/virology; Sequence Deletion; Vero Cells; Viral Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Herpesvirus 8, Human / Intracellular Signaling Peptides and Proteins / Phospholipase C gamma / Human Umbilical Vein Endothelial Cells / Muscle Proteins / Neovascularization, Pathologic Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2012 Type: Article Affiliation country: Germany

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