Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial.

Lopes, Renato D; Al-Khatib, Sana M; Wallentin, Lars; Yang, Hongqiu; Ansell, Jack; Bahit, M Cecilia; De Caterina, Raffaele; Dorian, Paul; Easton, J Donald; Erol, Cetin; Ezekowitz, Justin A; Gersh, Bernard J; Granger, Christopher B; Hohnloser, Stefan H; Horowitz, John; Hylek, Elaine M; McMurray, John J V; Mohan, Puneet; Vinereanu, Dragos; Alexander, John H

Lopes, Renato D; Al-Khatib, Sana M; Wallentin, Lars; Yang, Hongqiu; Ansell, Jack; Bahit, M Cecilia; De Caterina, Raffaele; Dorian, Paul; Easton, J Donald; Erol, Cetin; Ezekowitz, Justin A; Gersh, Bernard J; Granger, Christopher B; Hohnloser, Stefan H; Horowitz, John; Hylek, Elaine M; McMurray, John J V; Mohan, Puneet; Vinereanu, Dragos; Alexander, John H.

Affiliation

Lopes RD; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA. renato.lopes@duke.edu

Lancet ; 380(9855): 1749-58, 2012 Nov 17.

Article in En | MEDLINE | ID: mdl-23036896

Subject(s)

Anticoagulants/therapeutic use; Hemorrhage/prevention & control; Pyrazoles/therapeutic use; Pyridones/therapeutic use; Stroke/prevention & control; Warfarin/therapeutic use; Aged; Atrial Fibrillation/complications; Double-Blind Method; Embolism/prevention & control; Humans; Intracranial Hemorrhages/prevention & control; Male; Middle Aged; Risk Assessment/methods; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyridones / Warfarin / Stroke / Hemorrhage / Anticoagulants Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Humans / Male / Middle aged Language: En Journal: Lancet Year: 2012 Type: Article Affiliation country: United States

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