Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs.

Giampietro, Letizia; D'Angelo, Alessandra; Giancristofaro, Antonella; Ammazzalorso, Alessandra; De Filippis, Barbara; Fantacuzzi, Marialuigia; Linciano, Pasquale; Maccallini, Cristina; Amoroso, Rosa

Giampietro, Letizia; D'Angelo, Alessandra; Giancristofaro, Antonella; Ammazzalorso, Alessandra; De Filippis, Barbara; Fantacuzzi, Marialuigia; Linciano, Pasquale; Maccallini, Cristina; Amoroso, Rosa.

Affiliation

Giampietro L; Dipartimento di Farmacia, Università degli Studi G. d'Annunzio, via dei Vestini 31, 66100 Chieti, Italy.

Bioorg Med Chem Lett ; 22(24): 7662-6, 2012 Dec 15.

Article in En | MEDLINE | ID: mdl-23102891

Subject(s)

Clofibrate/pharmacology; PPAR alpha/agonists; PPAR gamma/agonists; Clofibrate/chemical synthesis; Clofibrate/chemistry; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Molecular Structure; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Clofibrate / PPAR alpha / PPAR gamma Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Type: Article Affiliation country: Italy

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