Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis.

Chen, Qin; Hongu, Tsunaki; Sato, Takanobu; Zhang, Yi; Ali, Wahida; Cavallo, Julie-Ann; van der Velden, Adrianus; Tian, Huasong; Di Paolo, Gilbert; Nieswandt, Bernhard; Kanaho, Yasunori; Frohman, Michael A

Chen, Qin; Hongu, Tsunaki; Sato, Takanobu; Zhang, Yi; Ali, Wahida; Cavallo, Julie-Ann; van der Velden, Adrianus; Tian, Huasong; Di Paolo, Gilbert; Nieswandt, Bernhard; Kanaho, Yasunori; Frohman, Michael A.

Affiliation

Chen Q; Department of Pharmacological Sciences and Center for Developmental Genetics, Stony Brook University, Stony Brook, NY 11794-5140, USA.

Sci Signal ; 5(249): ra79, 2012 Nov 06.

Article in En | MEDLINE | ID: mdl-23131846

Subject(s)

Breast Neoplasms/enzymology; Endothelial Cells/enzymology; Lung Neoplasms/enzymology; Neovascularization, Pathologic/enzymology; Phospholipase D/metabolism; Signal Transduction; Tumor Microenvironment; Animals; Breast Neoplasms/genetics; Breast Neoplasms/pathology; Cell Line, Tumor; Endothelial Cells/pathology; Female; Lung Neoplasms/genetics; Lung Neoplasms/pathology; Lung Neoplasms/secondary; Mice; Mice, Knockout; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic/genetics; Neovascularization, Pathologic/pathology; Phospholipase D/genetics; Transplantation, Heterologous

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phospholipase D / Breast Neoplasms / Signal Transduction / Endothelial Cells / Tumor Microenvironment / Lung Neoplasms / Neovascularization, Pathologic Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2012 Type: Article Affiliation country: United States

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