Diminished trkA receptor signaling reveals cholinergic-attentional vulnerability of aging.

Parikh, Vinay; Howe, William M; Welchko, Ryan M; Naughton, Sean X; D'Amore, Drew E; Han, Daniel H; Deo, Monika; Turner, David L; Sarter, Martin

Parikh, Vinay; Howe, William M; Welchko, Ryan M; Naughton, Sean X; D'Amore, Drew E; Han, Daniel H; Deo, Monika; Turner, David L; Sarter, Martin.

Affiliation

Parikh V; Department of Psychology and Neuroscience Program, Temple University, Philadelphia, PA 19122, USA.

Eur J Neurosci ; 37(2): 278-93, 2013 Jan.

Article in En | MEDLINE | ID: mdl-23228124

Subject(s)

Acetylcholine/metabolism; Aging/physiology; Attention; Cholinergic Neurons/metabolism; Receptor, trkA/metabolism; Age Factors; Animals; Basal Ganglia/metabolism; Basal Ganglia/physiology; Dependovirus/genetics; Genetic Vectors; Male; Nerve Growth Factors/genetics; Nerve Growth Factors/metabolism; Nerve Tissue Proteins; PC12 Cells; Protein Precursors/genetics; Protein Precursors/metabolism; RNA, Small Interfering; Rats; Rats, Wistar; Receptor, trkA/genetics; Receptors, Growth Factor; Receptors, Nerve Growth Factor/genetics; Receptors, Nerve Growth Factor/metabolism; Signal Transduction; Synapses/metabolism; Transcription, Genetic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Attention / Aging / Acetylcholine / Receptor, trkA / Cholinergic Neurons Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Neurosci Journal subject: NEUROLOGIA Year: 2013 Type: Article Affiliation country: United States

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