Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents.

Nguyen, C H; Lhoste, J M; Lavelle, F; Bissery, M C; Bisagni, E

Nguyen, C H; Lhoste, J M; Lavelle, F; Bissery, M C; Bisagni, E.

Affiliation

Nguyen CH; URA 1387 CNRS, U 219 INSERM, Institut Curie, Orsay, France.

J Med Chem ; 33(5): 1519-28, 1990 May.

Article in En | MEDLINE | ID: mdl-2329575

Subject(s)

Antineoplastic Agents/chemical synthesis; Pyridines/chemical synthesis; Animals; Chemical Phenomena; Chemistry; Leukemia, Experimental/drug therapy; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pyridines/therapeutic use; Structure-Activity Relationship; Tumor Cells, Cultured/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Antineoplastic Agents Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1990 Type: Article Affiliation country: France

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