Anti-platelet activity of erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan from Myristica fragrans.

Kang, Jung Won; Min, Byung-Sun; Lee, Jeong-Hyung

Kang, Jung Won; Min, Byung-Sun; Lee, Jeong-Hyung.

Affiliation

Kang JW; Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon-Do, 200-701, Republic of Korea.

Phytother Res ; 27(11): 1694-9, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23296979

Subject(s)

Blood Platelets/drug effects; Lignans/pharmacology; Myristica/chemistry; Platelet Aggregation Inhibitors/pharmacology; Adult; Arachidonic Acid/pharmacology; Calcium/metabolism; Calcium Signaling; Cyclic AMP/metabolism; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Male; Platelet Activating Factor/pharmacology; Platelet Activation/drug effects; Platelet Aggregation/drug effects; Serotonin/metabolism; Thrombin/pharmacology; Thromboxane B2/metabolism; Young Adult

Key words

Myristica fragrans; anti-platelet; neolignan; platelet-activating factor; thrombin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Platelet Aggregation Inhibitors / Lignans / Myristica Limits: Adult / Humans / Male Language: En Journal: Phytother Res Journal subject: TERAPIAS COMPLEMENTARES Year: 2013 Type: Article

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