Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations.

Wong, Nelson K Y; Fuller, Megan; Sung, Sandy; Wong, Fred; Karsan, Aly

Wong, Nelson K Y; Fuller, Megan; Sung, Sandy; Wong, Fred; Karsan, Aly.

Affiliation

Wong NK; Genome Sciences Centre, BC Cancer Agency Vancouver, BC, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia Vancouver, BC, Canada.

Cancer Med ; 1(2): 105-13, 2012 Oct.

Article in En | MEDLINE | ID: mdl-23342261

Subject(s)

Breast Neoplasms/metabolism; Carcinogenesis/genetics; Neoplastic Stem Cells/metabolism; Receptors, Notch/metabolism; Animals; CD24 Antigen/metabolism; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins/genetics; Female; Green Fluorescent Proteins/genetics; Humans; Hyaluronan Receptors/metabolism; Integrin alpha6/metabolism; MCF-7 Cells; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Receptors, Notch/genetics; Signal Transduction; Transcription Factors/genetics

Key words

Breast cancer; MCF-7; Notch; cancer stem cells; dominant-negative MAML

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Breast Neoplasms / Receptors, Notch / Carcinogenesis Limits: Animals / Female / Humans Language: En Journal: Cancer Med Year: 2012 Type: Article Affiliation country: Canada

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