A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel.

Xiao, Rui; Zhang, Bi; Dong, Yongming; Gong, Jianke; Xu, Tao; Liu, Jianfeng; Xu, X Z Shawn

Xiao, Rui; Zhang, Bi; Dong, Yongming; Gong, Jianke; Xu, Tao; Liu, Jianfeng; Xu, X Z Shawn.

Affiliation

Xiao R; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.

Cell ; 152(4): 806-17, 2013 Feb 14.

Article in En | MEDLINE | ID: mdl-23415228

Subject(s)

Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/genetics; Caenorhabditis elegans/metabolism; Calcium Channels/metabolism; Longevity; Nerve Tissue Proteins/metabolism; Thermosensing; Transient Receptor Potential Channels/metabolism; Aging; Animals; Animals, Genetically Modified; Calcium Channels/genetics; Calcium Signaling; Cold Temperature; Forkhead Transcription Factors; Humans; Intestinal Mucosa/metabolism; Nerve Tissue Proteins/genetics; Protein Kinase C/metabolism; Protein Serine-Threonine Kinases/metabolism; TRPA1 Cation Channel; Transcription Factors/metabolism; Transient Receptor Potential Channels/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thermosensing / Calcium Channels / Caenorhabditis elegans / Caenorhabditis elegans Proteins / Transient Receptor Potential Channels / Longevity / Nerve Tissue Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Year: 2013 Type: Article Affiliation country: United States

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