A novel snRNA-like transcript affects amyloidogenesis and cell cycle progression through perturbation of Fe65L1 (APBB2) alternative splicing.

Penna, Ilaria; Vassallo, Irene; Nizzari, Mario; Russo, Debora; Costa, Delfina; Menichini, Paola; Poggi, Alessandro; Russo, Claudio; Dieci, Giorgio; Florio, Tullio; Cancedda, Ranieri; Pagano, Aldo

Penna, Ilaria; Vassallo, Irene; Nizzari, Mario; Russo, Debora; Costa, Delfina; Menichini, Paola; Poggi, Alessandro; Russo, Claudio; Dieci, Giorgio; Florio, Tullio; Cancedda, Ranieri; Pagano, Aldo.

Affiliation

Penna I; Dept. of Experimental Medicine, University of Genova, Genova, Italy.

Biochim Biophys Acta ; 1833(6): 1511-26, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23485396

Subject(s)

Adaptor Proteins, Signal Transducing/genetics; Alternative Splicing; Amyloid beta-Protein Precursor/metabolism; Amyloidosis/genetics; Cell Cycle; Neuroblastoma/pathology; RNA, Small Nuclear/genetics; Adaptor Proteins, Signal Transducing/metabolism; Alzheimer Disease/genetics; Alzheimer Disease/metabolism; Alzheimer Disease/pathology; Amyloidosis/metabolism; Animals; Apoptosis; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Fluorescent Antibody Technique; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Micronucleus Tests; Neuroblastoma/genetics; Neuroblastoma/metabolism; Protein Binding; Protein Processing, Post-Translational; RNA, Messenger/genetics; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Small Nuclear / Cell Cycle / Amyloid beta-Protein Precursor / Alternative Splicing / Adaptor Proteins, Signal Transducing / Amyloidosis / Neuroblastoma Limits: Animals / Humans Language: En Journal: Biochim Biophys Acta Year: 2013 Type: Article Affiliation country: Italy

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