Estrogen receptor-ß ligand treatment after disease onset is neuroprotective in the multiple sclerosis model.

Wisdom, Amy J; Cao, Yuan; Itoh, Noriko; Spence, Rory D; Voskuhl, Rhonda R

Wisdom, Amy J; Cao, Yuan; Itoh, Noriko; Spence, Rory D; Voskuhl, Rhonda R.

Affiliation

Wisdom AJ; UCLA Multiple Sclerosis Program, Department of Neurology, University of California, Los Angeles, California 90095, USA.

J Neurosci Res ; 91(7): 901-8, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23633287

Subject(s)

Encephalomyelitis, Autoimmune, Experimental/drug therapy; Neuroprotective Agents/therapeutic use; Nitriles/therapeutic use; Propionates/therapeutic use; Receptors, Estrogen/agonists; Animals; Axons/drug effects; Demyelinating Diseases/etiology; Demyelinating Diseases/prevention & control; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental/chemically induced; Encephalomyelitis, Autoimmune, Experimental/complications; Female; Freund's Adjuvant/toxicity; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein/immunology; Peptide Fragments/immunology; Severity of Illness Index

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propionates / Receptors, Estrogen / Neuroprotective Agents / Encephalomyelitis, Autoimmune, Experimental / Nitriles Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Neurosci Res Year: 2013 Type: Article Affiliation country: United States

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