Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease.

Wu, Cheng Guo; Cheng, Shu Chun; Chen, Shiang Chuan; Li, Juo Yan; Fang, Yi Hsuan; Chen, Yau Hung; Chou, Chi Yuan

Wu, Cheng Guo; Cheng, Shu Chun; Chen, Shiang Chuan; Li, Juo Yan; Fang, Yi Hsuan; Chen, Yau Hung; Chou, Chi Yuan.

Affiliation

Wu CG; Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei 112, Taiwan.

Acta Crystallogr D Biol Crystallogr ; 69(Pt 5): 747-55, 2013 May.

Article in En | MEDLINE | ID: mdl-23633583

Subject(s)

Cysteine Endopeptidases/chemistry; Severe acute respiratory syndrome-related coronavirus/enzymology; Viral Matrix Proteins/chemistry; Viral Proteins/chemistry; Binding Sites; Coronavirus 3C Proteases; Coronavirus M Proteins; Crystallography, X-Ray; Cysteine Endopeptidases/genetics; Cysteine Endopeptidases/metabolism; Models, Molecular; Mutation; Protein Conformation; Protein Multimerization; Severe acute respiratory syndrome-related coronavirus/chemistry; Viral Matrix Proteins/genetics; Viral Matrix Proteins/metabolism; Viral Proteins/genetics; Viral Proteins/metabolism

Key words

SARS; SARS coronavirus; main protease

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Cysteine Endopeptidases / Viral Matrix Proteins / Severe acute respiratory syndrome-related coronavirus Language: En Journal: Acta Crystallogr D Biol Crystallogr Year: 2013 Type: Article Affiliation country: Taiwan

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