Clinical performance of an automated stool DNA assay for detection of colorectal neoplasia.

Lidgard, Graham P; Domanico, Michael J; Bruinsma, Janelle J; Light, James; Gagrat, Zubin D; Oldham-Haltom, Rebecca L; Fourrier, Keith D; Allawi, Hatim; Yab, Tracy C; Taylor, William R; Simonson, Julie A; Devens, Mary; Heigh, Russell I; Ahlquist, David A; Berger, Barry M

Lidgard, Graham P; Domanico, Michael J; Bruinsma, Janelle J; Light, James; Gagrat, Zubin D; Oldham-Haltom, Rebecca L; Fourrier, Keith D; Allawi, Hatim; Yab, Tracy C; Taylor, William R; Simonson, Julie A; Devens, Mary; Heigh, Russell I; Ahlquist, David A; Berger, Barry M.

Affiliation

Lidgard GP; Exact Sciences Corporation, Madison, Wisconsin.

Clin Gastroenterol Hepatol ; 11(10): 1313-8, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23639600

Subject(s)

Automation, Laboratory/methods; Biomarkers, Tumor/analysis; Colorectal Neoplasms/diagnosis; DNA/isolation & purification; Feces/chemistry; Hemoglobins/analysis; Molecular Diagnostic Techniques/methods; Adult; Aged; Aged, 80 and over; Case-Control Studies; DNA/genetics; Female; Humans; Male; Middle Aged; Sensitivity and Specificity; Single-Blind Method

Key words

AA; BMP3; CRC; Colon Cancer; Early Detection; FIT; HGD; Hb; NDRG4; QuARTS; SSA; advanced adenoma; colorectal cancer; fecal immunochemical test; hemoglobin; high-grade dysplasia; quantitative allele-specific real-time target and signal amplification; sDNA; sessile serrated adenoma ≥1-cm size; stool DNA

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Hemoglobins / Colorectal Neoplasms / Biomarkers, Tumor / Molecular Diagnostic Techniques / Feces / Automation, Laboratory Type of study: Clinical_trials / Diagnostic_studies / Evaluation_studies / Guideline / Observational_studies / Prognostic_studies / Screening_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Clin Gastroenterol Hepatol Journal subject: GASTROENTEROLOGIA Year: 2013 Type: Article

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