Innovative approach to produce submicron drug particles by vibrational atomization spray drying: influence of the type of solvent and surfactant.

Durli, T L; Dimer, F A; Fontana, M C; Pohlmann, A R; Beck, R C R; Guterres, S S

Durli, T L; Dimer, F A; Fontana, M C; Pohlmann, A R; Beck, R C R; Guterres, S S.

Affiliation

Durli TL; Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS) , Porto Alegre, RS , Brazil and.

Drug Dev Ind Pharm ; 40(8): 1011-20, 2014 Aug.

Article in En | MEDLINE | ID: mdl-23672183

Subject(s)

Dexamethasone/chemistry; Solvents/chemistry; Surface-Active Agents/chemistry; Technology, Pharmaceutical/methods; Excipients/chemistry; Microscopy, Electron, Scanning/methods; Particle Size; Powders/chemistry; Solutions/chemistry; Surface Properties; Surface Tension; Viscosity

Key words

Dexamethasone; Nano Spray Dryer; ionic surfactants; organic solution; submicrometric particles; vibrational atomization

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Solvents / Surface-Active Agents / Dexamethasone / Technology, Pharmaceutical Type of study: Prognostic_studies Language: En Journal: Drug Dev Ind Pharm Year: 2014 Type: Article

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