Glycochenodeoxycholic Acid/toxicity; Mitochondria, Liver/drug effects; Mitochondrial ADP, ATP Translocases/agonists; Taurochenodeoxycholic Acid/pharmacology; Animals; Cell Membrane Permeability/drug effects; Dose-Response Relationship, Drug; Liposomes/chemistry; Liver/chemistry; Membrane Potential, Mitochondrial/drug effects; Mitochondria, Heart/chemistry; Mitochondria, Liver/metabolism; Mitochondria, Liver/pathology; Mitochondrial ADP, ATP Translocases/isolation & purification; Mitochondrial Membrane Transport Proteins/agonists; Mitochondrial Membrane Transport Proteins/metabolism; Mitochondrial Membranes/chemistry; Mitochondrial Membranes/drug effects; Mitochondrial Permeability Transition Pore; Myocardium/chemistry; Rats; Taurochenodeoxycholic Acid/toxicity; Voltage-Dependent Anion Channels/chemistry; Voltage-Dependent Anion Channels/isolation & purification

4-MUP; 4-methylumbelliferyl phosphate; ANT; Bile salts; Cholestasis; Cys A; Cyt C; FCCP; GCDCA; IM; Liver; MMP; MOMP; MPT; Mitochondria; Mitochondrial permeability transition; MßCD; OD; OM; PC; ROS; Rh123; TCDCA; TUDCA; VDAC; ZE-FFE; adenine nucleotide translocator; carbonylcyanide-p-(trifluoromethoxy) phenyl-hydrazone; cyclosporine A; cytochrome C; glycochenodeoxycholic acid; inner membrane; methyl-ß-cyclodextrin; mitochondrial membrane potential; mitochondrial outer membrane rupture; mitochondrial permeability transition; optical density; outer membrane; phosphatidylcholine; reactive oxygen species; rhodamine 123; taurochenodeoxycholic acid; tauroursodeoxycholic acid; voltage-dependent anion channel; zone electrophoresis in a free flow electrophoresis device