A mechanistic understanding of allosteric immune escape pathways in the HIV-1 envelope glycoprotein.

Sethi, Anurag; Tian, Jianhui; Derdeyn, Cynthia A; Korber, Bette; Gnanakaran, S

Sethi, Anurag; Tian, Jianhui; Derdeyn, Cynthia A; Korber, Bette; Gnanakaran, S.

Affiliation

Sethi A; Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, USA.

PLoS Comput Biol ; 9(5): e1003046, 2013.

Article in En | MEDLINE | ID: mdl-23696718

Subject(s)

HIV Envelope Protein gp120; HIV-1; Immune Evasion/physiology; Molecular Dynamics Simulation; Binding Sites; CD4 Antigens/chemistry; CD4 Antigens/metabolism; Computational Biology; HIV Envelope Protein gp120/chemistry; HIV Envelope Protein gp120/metabolism; HIV Envelope Protein gp120/physiology; HIV Infections/virology; HIV-1/chemistry; HIV-1/metabolism; HIV-1/physiology; Humans; Principal Component Analysis; Protein Conformation; Reproducibility of Results; Structural Homology, Protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Envelope Protein gp120 / HIV-1 / Molecular Dynamics Simulation / Immune Evasion Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS Comput Biol Journal subject: BIOLOGIA / INFORMATICA MEDICA Year: 2013 Type: Article Affiliation country: United States

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