Antiandrogenic actions of medroxyprogesterone acetate on epithelial cells within normal human breast tissues cultured ex vivo.

Ochnik, Aleksandra M; Moore, Nicole L; Jankovic-Karasoulos, Tanja; Bianco-Miotto, Tina; Ryan, Natalie K; Thomas, Mervyn R; Birrell, Stephen N; Butler, Lisa M; Tilley, Wayne D; Hickey, Theresa E

Ochnik, Aleksandra M; Moore, Nicole L; Jankovic-Karasoulos, Tanja; Bianco-Miotto, Tina; Ryan, Natalie K; Thomas, Mervyn R; Birrell, Stephen N; Butler, Lisa M; Tilley, Wayne D; Hickey, Theresa E.

Affiliation

Ochnik AM; From the 1Dame Roma Mitchell Cancer Research Laboratories, Hanson Institute, Discipline of Medicine, Faculty of Health Sciences, University of Adelaide, Adelaide, SA, Australia; and 2Emphron Informatics, Toowong, QLD, Australia.

Menopause ; 21(1): 79-88, 2014 Jan.

Article in En | MEDLINE | ID: mdl-23715406

Subject(s)

Antineoplastic Agents, Hormonal/pharmacology; Breast/drug effects; Epithelial Cells/drug effects; Medroxyprogesterone Acetate/pharmacology; Androgen Antagonists/pharmacology; Androgens/pharmacology; Anilides/pharmacology; Breast/anatomy & histology; Breast/cytology; Bromodeoxyuridine/metabolism; Cell Proliferation/drug effects; Dihydrotestosterone/pharmacology; Epithelial Cells/physiology; Estrogen Receptor alpha/metabolism; Female; Humans; Ki-67 Antigen/metabolism; Nitriles/pharmacology; Postmenopause; Premenopause/physiology; Proto-Oncogene Proteins c-bcl-2/metabolism; Receptors, Androgen/metabolism; Receptors, Progesterone/metabolism; Signal Transduction/drug effects; Tissue Culture Techniques; Tosyl Compounds/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast / Medroxyprogesterone Acetate / Antineoplastic Agents, Hormonal / Epithelial Cells Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Menopause Journal subject: GINECOLOGIA Year: 2014 Type: Article Affiliation country: Australia

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