Noncanonical role of the PDZ4 domain of the adaptor protein PDZK1 in the regulation of the hepatic high density lipoprotein receptor scavenger receptor class B, type I (SR-BI).

Tsukamoto, Kosuke; Wales, Thomas E; Daniels, Kathleen; Pal, Rinku; Sheng, Ren; Cho, Wonhwa; Stafford, Walter; Engen, John R; Krieger, Monty; Kocher, Olivier

Tsukamoto, Kosuke; Wales, Thomas E; Daniels, Kathleen; Pal, Rinku; Sheng, Ren; Cho, Wonhwa; Stafford, Walter; Engen, John R; Krieger, Monty; Kocher, Olivier.

Affiliation

Tsukamoto K; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

J Biol Chem ; 288(27): 19845-60, 2013 Jul 05.

Article in En | MEDLINE | ID: mdl-23720744

Subject(s)

Cell Membrane/metabolism; Hepatocytes/metabolism; Intracellular Signaling Peptides and Proteins/metabolism; PDZ Domains/physiology; Scavenger Receptors, Class B/metabolism; Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Membrane/chemistry; Cell Membrane/genetics; Cells, Cultured; Deuterium Exchange Measurement; Hepatocytes/chemistry; Hepatocytes/cytology; Humans; Intracellular Signaling Peptides and Proteins/chemistry; Intracellular Signaling Peptides and Proteins/genetics; Membrane Proteins; Mice; Mice, Knockout; Mutation, Missense; Protein Binding/physiology; Scavenger Receptors, Class B/chemistry; Scavenger Receptors, Class B/genetics; Sequence Deletion; Surface Plasmon Resonance

Key words

Cholesterol Metabolism; High Density Lipoprotein (HDL); Protein-Protein Interactions; Receptors; Transgenic Mice

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Membrane / Hepatocytes / Intracellular Signaling Peptides and Proteins / Scavenger Receptors, Class B / PDZ Domains Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2013 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google