Three dimensional quantitative structure-activity relationship of 5H-Pyrido[4,3-b]indol-4-carboxamide JAK2 inhibitors.

Wu, Xiaoyun; Wan, Shanhe; Zhang, Jiajie

Wu, Xiaoyun; Wan, Shanhe; Zhang, Jiajie.

Affiliation

Wu X; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China. xywugz@163.com.

Int J Mol Sci ; 14(6): 12037-53, 2013 Jun 05.

Article in En | MEDLINE | ID: mdl-23739681

Subject(s)

Indoles/chemistry; Indoles/pharmacology; Janus Kinase 2/antagonists & inhibitors; Models, Molecular; Protein Kinase Inhibitors/chemistry; Protein Kinase Inhibitors/pharmacology; Quantitative Structure-Activity Relationship; Drug Design; Inhibitory Concentration 50; Janus Kinase 2/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Models, Molecular / Quantitative Structure-Activity Relationship / Protein Kinase Inhibitors / Janus Kinase 2 / Indoles Type of study: Prognostic_studies Language: En Journal: Int J Mol Sci Year: 2013 Type: Article Affiliation country: China

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