CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization, and is a marker for poor prognosis in acute myeloid leukemia.

Brault, L; Rovó, A; Decker, S; Dierks, C; Tzankov, A; Schwaller, J

Brault, L; Rovó, A; Decker, S; Dierks, C; Tzankov, A; Schwaller, J.

Affiliation

Brault L; Department of Biomedicine, University Children's Hospital (UKBB), University of Basel, Basel, Switzerland.
Rovó A; Department of Hematology, University Hospital Basel, Basel, Switzerland.
Decker S; Department of Hematology/Oncology, University Medical Center Freiburg, Freiburg, Germany.
Dierks C; Department of Hematology/Oncology, University Medical Center Freiburg, Freiburg, Germany.
Tzankov A; Institute for Pathology, University Hospital Basel, Basel, Switzerland.
Schwaller J; Department of Biomedicine, University Children's Hospital (UKBB), University of Basel, Basel, Switzerland.

Leukemia ; 28(3): 566-76, 2014 Mar.

Article in En | MEDLINE | ID: mdl-23817178

Subject(s)

Biomarkers/metabolism; Cell Adhesion/physiology; Leukemia, Myeloid, Acute/pathology; Receptors, CXCR4/physiology; Serine/chemistry; Adult; Aged; Aged, 80 and over; Biomarkers/chemistry; Female; Humans; Male; Middle Aged; Mutation; Prognosis; Receptors, CXCR4/chemistry; Receptors, CXCR4/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine / Biomarkers / Leukemia, Myeloid, Acute / Cell Adhesion / Receptors, CXCR4 Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2014 Type: Article Affiliation country: Switzerland

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