Rome III functional constipation and irritable bowel syndrome with constipation are similar disorders within a spectrum of sensitization, regulated by serotonin.

Shekhar, Chander; Monaghan, Phillip J; Morris, Julie; Issa, Basma; Whorwell, Peter J; Keevil, Brian; Houghton, Lesley A

Shekhar, Chander; Monaghan, Phillip J; Morris, Julie; Issa, Basma; Whorwell, Peter J; Keevil, Brian; Houghton, Lesley A.

Affiliation

Shekhar C; Neurogastroenterology Unit, University of Manchester, Manchester, UK.

Gastroenterology ; 145(4): 749-57; quiz e13-4, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23872499

Subject(s)

Constipation/physiopathology; Irritable Bowel Syndrome/physiopathology; Serotonin/physiology; Adult; Constipation/etiology; Female; Gastrointestinal Transit; Humans; Irritable Bowel Syndrome/etiology; Middle Aged; Sensory Thresholds; Serotonin/blood

Key words

5-HT; 5-Hydroxytryptamine; 5-hydroxytryptamine; EC; FC; HV; IBS-C; IBS-D; Neurotransmitter; PDP; SSRI; Visceral Sensitivity; enterochromaffin; functional constipation; healthy volunteer; irritable bowel syndrome with constipation; irritable bowel syndrome with diarrhea; platelet-depleted plasma; selective serotonin reuptake inhibitor

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serotonin / Constipation / Irritable Bowel Syndrome Type of study: Etiology_studies Limits: Adult / Female / Humans / Middle aged Language: En Journal: Gastroenterology Year: 2013 Type: Article Affiliation country: United kingdom

Fulltext

XML

PubMed Links

Search on Google