Reciprocal modulation of C/EBP-&#945; and C/EBP-ß by IL-13 in activated microglia prevents neuronal death.

Pan, Hung Chuan; Yang, Cheng Ning; Hung, Yi Wen; Lee, Wen Jane; Tien, Hsing Ru; Shen, Chin Chang; Sheehan, Jason; Chou, Chiang Ting; Sheu, Meei Ling

Reciprocal modulation of C/EBP-α and C/EBP-ß by IL-13 in activated microglia prevents neuronal death.

Pan, Hung Chuan; Yang, Cheng Ning; Hung, Yi Wen; Lee, Wen Jane; Tien, Hsing Ru; Shen, Chin Chang; Sheehan, Jason; Chou, Chiang Ting; Sheu, Meei Ling.

Affiliation

Pan HC; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Neurosurgery, Taichung Veterans General Hospital, Taichung, Taiwan.

Eur J Immunol ; 43(11): 2854-65, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23881867

Subject(s)

Apoptosis; CCAAT-Enhancer-Binding Protein-beta/metabolism; CCAAT-Enhancer-Binding Proteins/metabolism; Interleukin-13/metabolism; Microglia/metabolism; Neurons/physiology; Animals; CCAAT-Enhancer-Binding Protein-beta/biosynthesis; CCAAT-Enhancer-Binding Protein-beta/genetics; CCAAT-Enhancer-Binding Proteins/biosynthesis; CCAAT-Enhancer-Binding Proteins/genetics; Calpain/metabolism; Caspase 12/metabolism; Cells, Cultured; Cyclooxygenase 2/metabolism; Dinoprostone/biosynthesis; Heme Oxygenase-1/biosynthesis; Lipopolysaccharides; Membrane Proteins/biosynthesis; PPAR gamma/metabolism; RNA Interference; RNA, Small Interfering; Rats; Signal Transduction

Key words

C/EBP; IL-13; Microglia; Neuron

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Microglia / Interleukin-13 / CCAAT-Enhancer-Binding Proteins / CCAAT-Enhancer-Binding Protein-beta / Neurons Limits: Animals Language: En Journal: Eur J Immunol Year: 2013 Type: Article Affiliation country: Taiwan

Fulltext

XML

PubMed Links

Search on Google