Kindlin-2 regulates hemostasis by controlling endothelial cell-surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism.

Pluskota, Elzbieta; Ma, Yi; Bledzka, Kamila M; Bialkowska, Katarzyna; Soloviev, Dmitry A; Szpak, Dorota; Podrez, Eugene A; Fox, Paul L; Hazen, Stanley L; Dowling, James J; Ma, Yan-Qing; Plow, Edward F

Pluskota, Elzbieta; Ma, Yi; Bledzka, Kamila M; Bialkowska, Katarzyna; Soloviev, Dmitry A; Szpak, Dorota; Podrez, Eugene A; Fox, Paul L; Hazen, Stanley L; Dowling, James J; Ma, Yan-Qing; Plow, Edward F.

Affiliation

Pluskota E; Joseph J. Jacobs Center for Thrombosis and Vascular Biology, Department of Molecular Cardiology, and.

Blood ; 122(14): 2491-9, 2013 Oct 03.

Article in En | MEDLINE | ID: mdl-23896409

Subject(s)

Blood Platelets/metabolism; Clathrin/metabolism; Cytoskeletal Proteins/metabolism; Endothelial Cells/metabolism; Hemostasis/physiology; Muscle Proteins/metabolism; 5'-Nucleotidase/biosynthesis; Adenosine Diphosphate/metabolism; Adenosine Monophosphate/metabolism; Animals; Antigens, CD/biosynthesis; Apyrase/biosynthesis; Cell Membrane/metabolism; Female; Flow Cytometry; Immunoprecipitation; Male; Mice; Mice, Knockout; Platelet Aggregation/physiology; Protein Transport/physiology; Surface Plasmon Resonance

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Clathrin / Cytoskeletal Proteins / Endothelial Cells / Hemostasis / Muscle Proteins Limits: Animals Language: En Journal: Blood Year: 2013 Type: Article

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