Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin.

Bolinder, J; Ljunggren, Ö; Johansson, L; Wilding, J; Langkilde, A M; Sjöström, C D; Sugg, J; Parikh, S

Bolinder, J; Ljunggren, Ö; Johansson, L; Wilding, J; Langkilde, A M; Sjöström, C D; Sugg, J; Parikh, S.

Affiliation

Bolinder J; Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital Huddinge, Karolinska Institute, Stockholm, Sweden.

Diabetes Obes Metab ; 16(2): 159-69, 2014 Feb.

Article in En | MEDLINE | ID: mdl-23906445

Subject(s)

Benzhydryl Compounds/therapeutic use; Blood Glucose/metabolism; Diabetes Mellitus, Type 2/drug therapy; Glucosides/therapeutic use; Glycated Hemoglobin/metabolism; Metformin/therapeutic use; Sodium-Glucose Transporter 2 Inhibitors; Weight Loss/drug effects; Absorptiometry, Photon; Benzhydryl Compounds/pharmacokinetics; Blood Glucose/drug effects; Body Mass Index; Bone Density/drug effects; Diabetes Mellitus, Type 2/blood; Diabetes Mellitus, Type 2/complications; Double-Blind Method; Female; Glucosides/pharmacokinetics; Glycated Hemoglobin/drug effects; Humans; Male; Metformin/pharmacokinetics; Sodium-Glucose Transporter 2; Treatment Outcome

Key words

SGLT2 inhibitor; adipose tissue; bone mineral density; fat; metformin; randomized trial; type 2 diabetes

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzhydryl Compounds / Blood Glucose / Glycated Hemoglobin / Weight Loss / Diabetes Mellitus, Type 2 / Sodium-Glucose Transporter 2 Inhibitors / Glucosides / Metformin Type of study: Clinical_trials Limits: Female / Humans / Male Language: En Journal: Diabetes Obes Metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2014 Type: Article Affiliation country: Sweden

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