Sputum cytokine mapping reveals an 'IL-5, IL-17A, IL-25-high' pattern associated with poorly controlled asthma.

Seys, S F; Grabowski, M; Adriaensen, W; Decraene, A; Dilissen, E; Vanoirbeek, J A; Dupont, L J; Ceuppens, J L; Bullens, D M A

Seys, S F; Grabowski, M; Adriaensen, W; Decraene, A; Dilissen, E; Vanoirbeek, J A; Dupont, L J; Ceuppens, J L; Bullens, D M A.

Affiliation

Seys SF; Pneumology, Department of Clinical and Experimental Medicine, Catholic University of Leuven (KU Leuven), Leuven, Belgium.

Clin Exp Allergy ; 43(9): 1009-17, 2013 Sep.

Article in En | MEDLINE | ID: mdl-23957336

Subject(s)

Asthma/genetics; Interleukin-17/genetics; Interleukin-5/genetics; Sputum/chemistry; Adult; Asthma/drug therapy; Asthma/immunology; Case-Control Studies; Cytokines/genetics; Cytokines/immunology; Female; Gene Expression Regulation; Humans; Interleukin-17/immunology; Interleukin-5/immunology; Male; Middle Aged; Risk Factors; Sputum/immunology; Th2 Cells/immunology; Th2 Cells/metabolism; Transcriptome; Treatment Outcome; Young Adult

Key words

airway inflammation; asthma control; asthma phenotyping; cytokine; induced sputum

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Sputum / Interleukin-5 / Interleukin-17 Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Exp Allergy Journal subject: ALERGIA E IMUNOLOGIA Year: 2013 Type: Article Affiliation country: Belgium

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