Caloric restriction modulates Mcl-1 expression and sensitizes lymphomas to BH3 mimetic in mice.

Meynet, Ophélie; Zunino, Barbara; Happo, Lina; Pradelli, Ludivine A; Chiche, Johanna; Jacquin, Marie A; Mondragón, Laura; Tanti, Jean-François; Taillan, Bruno; Garnier, Georges; Reverso-Meinietti, Julie; Mounier, Nicolas; Michiels, Jean-François; Michalak, Ewa M; Carles, Michel; Scott, Clare L; Ricci, Jean-Ehrland

Meynet, Ophélie; Zunino, Barbara; Happo, Lina; Pradelli, Ludivine A; Chiche, Johanna; Jacquin, Marie A; Mondragón, Laura; Tanti, Jean-François; Taillan, Bruno; Garnier, Georges; Reverso-Meinietti, Julie; Mounier, Nicolas; Michiels, Jean-François; Michalak, Ewa M; Carles, Michel; Scott, Clare L; Ricci, Jean-Ehrland.

Affiliation

Meynet O; Centre Méditerranéen de Médecine Moléculaire (C3M), équipe "contrôle métabolique des morts cellulaires," Institut national de la santé et de la recherche médicale (Inserm) U1065, Nice, France;

Blood ; 122(14): 2402-11, 2013 Oct 03.

Article in En | MEDLINE | ID: mdl-23966420

Subject(s)

Caloric Restriction; Drug Resistance, Neoplasm/physiology; Lymphoma, B-Cell/metabolism; Proto-Oncogene Proteins c-bcl-2/biosynthesis; Animals; Antineoplastic Agents/pharmacology; Apoptosis/drug effects; BH3 Interacting Domain Death Agonist Protein/metabolism; Biphenyl Compounds/pharmacology; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols/pharmacology; Piperazines/pharmacology; Sulfonamides/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, B-Cell / Drug Resistance, Neoplasm / Proto-Oncogene Proteins c-bcl-2 / Caloric Restriction Type of study: Prognostic_studies Limits: Animals Language: En Journal: Blood Year: 2013 Type: Article

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