Developing a rapid throughput screen for detection of nematicidal activity of plant cysteine proteinases: the role of Caenorhabditis elegans cystatins.

Phiri, A M; De Pomerai, D; Buttle, D J; Behnke, J M B

Phiri, A M; De Pomerai, D; Buttle, D J; Behnke, J M B.

Affiliation

Phiri AM; School of Biology, University of Nottingham, Nottingham, NG7 2RD, UK.
De Pomerai D; School of Biology, University of Nottingham, Nottingham, NG7 2RD, UK.
Buttle DJ; Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, S10 2RX, UK.
Behnke JM; School of Biology, University of Nottingham, Nottingham, NG7 2RD, UK.

Parasitology ; 141(2): 164-80, 2014 Feb.

Article in En | MEDLINE | ID: mdl-24001183

Subject(s)

Antinematodal Agents/pharmacology; Caenorhabditis elegans/drug effects; Carica/enzymology; Cystatins/metabolism; Cysteine Proteases/pharmacology; Cysteine Proteinase Inhibitors/metabolism; Animals; Caenorhabditis elegans/cytology; Caenorhabditis elegans/genetics; Caenorhabditis elegans/physiology; Caenorhabditis elegans Proteins/genetics; Caenorhabditis elegans Proteins/metabolism; Carica/chemistry; Cystatins/genetics; Cysteine Proteinase Inhibitors/genetics; Dose-Response Relationship, Drug; Genes, Reporter; Latex/isolation & purification; Latex/pharmacology; Leucine/analogs & derivatives; Leucine/genetics; Leucine/metabolism; Mutation; Organ Specificity; Plant Proteins/pharmacology; Recombinant Fusion Proteins; Temperature; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cystatins / Cysteine Proteinase Inhibitors / Caenorhabditis elegans / Carica / Cysteine Proteases / Antinematodal Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Parasitology Year: 2014 Type: Article Affiliation country: United kingdom

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