ß-Cell adaptation in a mouse model of glucocorticoid-induced metabolic syndrome.

Fransson, Liselotte; Franzén, Stephanie; Rosengren, Victoria; Wolbert, Petra; Sjöholm, Åke; Ortsäter, Henrik

Fransson, Liselotte; Franzén, Stephanie; Rosengren, Victoria; Wolbert, Petra; Sjöholm, Åke; Ortsäter, Henrik.

Affiliation

Fransson L; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, SE-118 83 Stockholm, Sweden Division of Drug Research, Experimental Renal Medicine, Department of Medical and Health Sciences Center of Medical Image Science and Visualization, Linköping University, SE-581 83 Linköping, Sweden Department of Biochemistry and Molecular Biology, College of Medicine, University of South Alabama, Mobile, Alabama 36688, USA.

J Endocrinol ; 219(3): 231-41, 2013 Dec.

Article in En | MEDLINE | ID: mdl-24048967

Subject(s)

Allostasis; Disease Models, Animal; Insulin-Secreting Cells/metabolism; Metabolic Syndrome/etiology; Stress, Physiological; Stress, Psychological/physiopathology; Adiposity; Administration, Oral; Animals; Behavior, Animal; Dyslipidemias/etiology; Energy Intake; Glucocorticoids/administration & dosage; Insulin Resistance; Insulin-Secreting Cells/pathology; Liver/metabolism; Liver/pathology; Male; Metabolic Syndrome/metabolism; Metabolic Syndrome/physiopathology; Mice; Mice, Inbred C57BL; Muscle, Skeletal/metabolism; Muscle, Skeletal/pathology; Weight Gain

Key words

diabetes; glucocorticoid; insulin secretion; islet cells; obesity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Stress, Psychological / Metabolic Syndrome / Disease Models, Animal / Insulin-Secreting Cells / Allostasis Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Endocrinol Year: 2013 Type: Article Affiliation country: United States

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