Calcium-Binding Proteins/metabolism; Genetic Therapy; Hypertension, Pulmonary/prevention & control; Intercellular Signaling Peptides and Proteins/metabolism; Membrane Proteins/metabolism; Muscle, Smooth, Vascular/metabolism; Myocytes, Smooth Muscle/metabolism; Receptors, Notch/metabolism; Signal Transduction; Adenoviridae/genetics; Animals; Binding Sites; Calcium-Binding Proteins/genetics; Cell Differentiation; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Genetic Therapy/methods; Genetic Vectors; Hypertension, Pulmonary/etiology; Hypertension, Pulmonary/genetics; Hypertension, Pulmonary/metabolism; Hypertension, Pulmonary/pathology; Hypoxia/complications; Intercellular Signaling Peptides and Proteins/genetics; Jagged-1 Protein; Male; Membrane Proteins/genetics; Mice, Inbred C57BL; Monocrotaline; Muscle, Smooth, Vascular/pathology; Myocytes, Smooth Muscle/pathology; Nuclear Proteins/metabolism; Phenotype; Promoter Regions, Genetic; Pulmonary Artery/metabolism; Pulmonary Artery/pathology; Rats; Rats, Sprague-Dawley; Receptor, Notch1/metabolism; Receptor, Notch3; Serrate-Jagged Proteins; Time Factors; Trans-Activators/metabolism; Transduction, Genetic; Transfection

hypertension, pulmonary; phenotype; smooth muscle cells