Phase II study of dovitinib in patients with metastatic and/or unresectable gastrointestinal stromal tumours after failure of imatinib and sunitinib.

Kang, Y-K; Yoo, C; Ryoo, B-Y; Lee, J J; Tan, E; Park, I; Park, J H; Choi, Y J; Jo, J; Ryu, J-S; Ryu, M-H

Kang, Y-K; Yoo, C; Ryoo, B-Y; Lee, J J; Tan, E; Park, I; Park, J H; Choi, Y J; Jo, J; Ryu, J-S; Ryu, M-H.

Affiliation

Kang YK; Department of Oncology and Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Br J Cancer ; 109(9): 2309-15, 2013 Oct 29.

Article in En | MEDLINE | ID: mdl-24084771

Subject(s)

Benzimidazoles/administration & dosage; Gastrointestinal Stromal Tumors/drug therapy; Quinolones/administration & dosage; Administration, Oral; Adult; Aged; Antineoplastic Agents/adverse effects; Antineoplastic Agents/pharmacokinetics; Antineoplastic Agents/therapeutic use; Benzamides/therapeutic use; Benzimidazoles/adverse effects; Benzimidazoles/pharmacokinetics; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors/metabolism; Humans; Imatinib Mesylate; Indoles/therapeutic use; Male; Middle Aged; Piperazines/therapeutic use; Prospective Studies; Protein Kinase Inhibitors/adverse effects; Protein Kinase Inhibitors/pharmacokinetics; Protein Kinase Inhibitors/therapeutic use; Pyrimidines/therapeutic use; Pyrroles/therapeutic use; Quinolones/adverse effects; Quinolones/pharmacokinetics; Sunitinib

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Quinolones / Gastrointestinal Stromal Tumors Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2013 Type: Article

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