The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma.

Weissinger, Daniel; Tagscherer, Katrin E; Macher-Göppinger, Stephan; Haferkamp, Axel; Wagener, Nina; Roth, Wilfried

Weissinger, Daniel; Tagscherer, Katrin E; Macher-Göppinger, Stephan; Haferkamp, Axel; Wagener, Nina; Roth, Wilfried.

Affiliation

Weissinger D; Molecular Tumor-Pathology, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. Wilfried.Roth@med.uni-heidelberg.de.

Mol Cancer ; 12(1): 120, 2013 Oct 10.

Article in En | MEDLINE | ID: mdl-24107265

Subject(s)

Carcinoma, Renal Cell/metabolism; Cell Movement; Kidney Neoplasms/metabolism; Phosphatidylinositol 3-Kinases/physiology; Receptors, Tumor Necrosis Factor, Member 6b/metabolism; Carcinoma, Renal Cell/pathology; Cell Adhesion; Cell Line, Tumor; Chromones/pharmacology; Fibronectins/metabolism; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HEK293 Cells; Humans; Kidney Neoplasms/pathology; Morpholines/pharmacology; NFATC Transcription Factors/metabolism; Neoplasm Invasiveness; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt/metabolism; RNA, Small Interfering/genetics; Receptors, Tumor Necrosis Factor, Member 6b/genetics; Signal Transduction; Transcription, Genetic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Cell Movement / Phosphatidylinositol 3-Kinases / Receptors, Tumor Necrosis Factor, Member 6b / Kidney Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2013 Type: Article Affiliation country: Germany

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