A structure-guided mutation in the major capsid protein retargets BK polyomavirus.

Neu, Ursula; Allen, Stacy-Ann A; Blaum, Bärbel S; Liu, Yan; Frank, Martin; Palma, Angelina S; Ströh, Luisa J; Feizi, Ten; Peters, Thomas; Atwood, Walter J; Stehle, Thilo

Neu, Ursula; Allen, Stacy-Ann A; Blaum, Bärbel S; Liu, Yan; Frank, Martin; Palma, Angelina S; Ströh, Luisa J; Feizi, Ten; Peters, Thomas; Atwood, Walter J; Stehle, Thilo.

Affiliation

Neu U; Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.

PLoS Pathog ; 9(10): e1003688, 2013.

Article in En | MEDLINE | ID: mdl-24130487

Subject(s)

BK Virus/metabolism; Capsid Proteins/metabolism; Gangliosides/metabolism; Mutation; Polyomavirus Infections/metabolism; Receptors, Virus/metabolism; BK Virus/chemistry; BK Virus/genetics; Capsid Proteins/chemistry; Capsid Proteins/genetics; Gangliosides/chemistry; Gangliosides/genetics; HEK293 Cells; Humans; Polyomavirus Infections/genetics; Protein Structure, Tertiary; Receptors, Virus/chemistry; Receptors, Virus/genetics; Simian virus 40/chemistry; Simian virus 40/genetics; Simian virus 40/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Virus / BK Virus / Polyomavirus Infections / Capsid Proteins / Gangliosides / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS Pathog Year: 2013 Type: Article Affiliation country: Germany

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