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A novel and photostable pH probe for selectively staining nuclei in living cells.
Zeng, Lintao; Fan, Ne; Zha, Jiayu; Hu, Xichao; Fu, Boqiao; Qin, Caiqin; Wang, Liang.
Affiliation
  • Zeng L; Department of Chemistry and Material Sciences, Hubei Engineering University, Xiaogan 432000, P. R. China. zlt1981@126.com.
Analyst ; 138(23): 7083-6, 2013 Dec 07.
Article in En | MEDLINE | ID: mdl-24131015
ABSTRACT
A novel pH probe based on hemi-cyanine was synthesized, which displays extremely large Stokes shift (122 nm) and good photostability. The probe responds to basic pH (pKa 8.32) with a colorimetric and fluorescence turn-on signal. Interestingly, the probe has good cell membrane permeability and could selectively stain nuclei in living cells.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Molecular Probes / Cell Nucleus / Coloring Agents / Hydrogen-Ion Concentration Language: En Journal: Analyst Year: 2013 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Molecular Probes / Cell Nucleus / Coloring Agents / Hydrogen-Ion Concentration Language: En Journal: Analyst Year: 2013 Type: Article