Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells - up regulation of Nrf2 expression and down regulation of NF-κB and COX-2.
Biochim Biophys Acta
; 1840(1): 681-92, 2014 Jan.
Article
in En
| MEDLINE
| ID: mdl-24161694
Key words
2,7-dichlorodihydrofluorescein diacetate; 2,7-dichlorofluorescein; 3,30-di-hexyloxacarbocyanine iodide; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; 4,4-diamidino-2-phenylindole; ANOVA; AO/EB; ARE; Acridine orange/ethidium bromide; Analysis of variance; Antioxidant responsive element; CAT; CBMN; CCCP; COX-2; Carbonyl cyanide m-chlorophenylhydrazone; Catalase; Cyclooxygenase-2; Cytokinesis block micronucleus assay; DAB; DAPI; DCF; DCF-DA; DMEM; DNA damage; DTT; DiOC6; Diaminobenzidine; Dithiothreitol; Dulbecco's modified Eagle's medium; EDTA; Ethylenediamine tetraacetic acid; FBS; Fetal bovine serum; GPx; GSH; GST; Glutathione; Glutathione S transferase; Glutathione peroxidase; IC20; Inducible nitric oxide synthase; Inflammation; Inhibitory concentration 20; Intracellular calcium level; LDH; LPO; LPS; Lactate dehydrogenase; Lipid peroxidation; Lipopolysaccharide; MN; MTT; Micronucleus; NF-κB; NO; Nitric oxide; Nrf-2; Nuclear factor E2 p45-related factor 2; Nuclear factor-kappa B; OPT; OTA; Ochratoxin; Ortho-phthalaldehyde; Oxidative stress; PCC; PMSF; Phenyl methyl sulfonyl fluoride; Protein carbonyl content; Quercetin; ROS; Reactive oxygen species; SOD; Superoxide dismutase; [Ca(2+)](i); iNOS
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Quercetin
/
Gene Expression Regulation, Neoplastic
/
NF-kappa B
/
Oxidative Stress
/
Cyclooxygenase 2
/
NF-E2-Related Factor 2
/
Antioxidants
/
Ochratoxins
Limits:
Humans
Language:
En
Journal:
Biochim Biophys Acta
Year:
2014
Type:
Article
Affiliation country:
India