[Cytosine deaminase and thymidine kinase double suicide gene system driven by carcinoembryonic antigen promoter for the treatment of colorectal carcinoma xenograft in nude mice].

Huang, Zheng-jie; Feng, Qing-zhao; You, Jun; Xu, Lin; Luo, Wei-yuan; Yi, Wen-cheng; Zeng, Yue-yue; Luo, Qi

[Cytosine deaminase and thymidine kinase double suicide gene system driven by carcinoembryonic antigen promoter for the treatment of colorectal carcinoma xenograft in nude mice].

Huang, Zheng-jie; Feng, Qing-zhao; You, Jun; Xu, Lin; Luo, Wei-yuan; Yi, Wen-cheng; Zeng, Yue-yue; Luo, Qi.

Affiliation

Huang ZJ; Department of Surgical Oncology, First Affiliated Hospital, Xiamen University & Xiamen Cancer Center, Xiamen 361003, China.

Zhonghua Yi Xue Za Zhi ; 93(28): 2235-40, 2013 Jul 23.

Article in Zh | MEDLINE | ID: mdl-24169337

Subject(s)

Carcinoembryonic Antigen/genetics; Colorectal Neoplasms/therapy; Cytosine Deaminase/genetics; Promoter Regions, Genetic; Thymidine Kinase/genetics; Animals; Colorectal Neoplasms/genetics; Flucytosine; Ganciclovir; Genetic Therapy; HeLa Cells; Humans; Injections, Intralesional; Mice; Mice, Nude; Transfection; Xenograft Model Antitumor Assays

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Collection: 01-internacional Database: MEDLINE Main subject: Thymidine Kinase / Colorectal Neoplasms / Carcinoembryonic Antigen / Promoter Regions, Genetic / Cytosine Deaminase Type of study: Clinical_trials Limits: Animals / Humans Language: Zh Journal: Zhonghua Yi Xue Za Zhi Year: 2013 Type: Article Affiliation country: China

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