An insight on human skin penetration of diflunisal: lipogel versus hydrogel microemulsion.

Sallam, Marwa Ahmed; Motawaa, Adel Mohamed; Mortada, Sana Mohamed

Sallam, Marwa Ahmed; Motawaa, Adel Mohamed; Mortada, Sana Mohamed.

Affiliation

Sallam MA; Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University , Alexandria , Egypt.

Drug Dev Ind Pharm ; 41(1): 141-7, 2015 Jan.

Article in En | MEDLINE | ID: mdl-24171693

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/metabolism; Diflunisal/metabolism; Emulsions/metabolism; Hydrogel, Polyethylene Glycol Dimethacrylate/metabolism; Lecithins/metabolism; Skin Absorption/physiology; Administration, Cutaneous; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Anti-Inflammatory Agents, Non-Steroidal/chemistry; Diflunisal/administration & dosage; Diflunisal/chemistry; Emulsions/administration & dosage; Emulsions/chemistry; Female; Gels; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate/administration & dosage; Hydrogel, Polyethylene Glycol Dimethacrylate/chemistry; Lecithins/administration & dosage; Lecithins/chemistry; Middle Aged; Organ Culture Techniques; Skin Absorption/drug effects

Key words

Butyl lactate; diflunisal; human skin; lecithin; microemulsion-based gel; organogel; transdermal

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Absorption / Anti-Inflammatory Agents, Non-Steroidal / Diflunisal / Hydrogel, Polyethylene Glycol Dimethacrylate / Emulsions / Lecithins Limits: Female / Humans / Middle aged Language: En Journal: Drug Dev Ind Pharm Year: 2015 Type: Article Affiliation country: Egypt

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