Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma.

Busse, William W; Holgate, Stephen; Kerwin, Edward; Chon, Yun; Feng, Jingyuan; Lin, Joseph; Lin, Shao-Lee

Busse, William W; Holgate, Stephen; Kerwin, Edward; Chon, Yun; Feng, Jingyuan; Lin, Joseph; Lin, Shao-Lee.

Affiliation

Busse WW; 1 University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Am J Respir Crit Care Med ; 188(11): 1294-302, 2013 Dec 01.

Article in En | MEDLINE | ID: mdl-24200404

Subject(s)

Antibodies, Monoclonal/therapeutic use; Asthma/drug therapy; Bronchi/drug effects; Receptors, Interleukin-17/drug effects; Adolescent; Adult; Aged; Antibodies, Monoclonal/administration & dosage; Antibodies, Monoclonal/adverse effects; Antibodies, Monoclonal, Humanized; Double-Blind Method; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Receptors, Interleukin-17/antagonists & inhibitors; Receptors, Interleukin-17/physiology; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Bronchi / Receptors, Interleukin-17 / Antibodies, Monoclonal Type of study: Clinical_trials / Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Am J Respir Crit Care Med Journal subject: TERAPIA INTENSIVA Year: 2013 Type: Article

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