IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes.

Diaz-de-Durana, Yaiza; Lau, Janet; Knee, Deborah; Filippi, Christophe; Londei, Marco; McNamara, Peter; Nasoff, Marc; DiDonato, Michael; Glynne, Richard; Herman, Ann E

Diaz-de-Durana, Yaiza; Lau, Janet; Knee, Deborah; Filippi, Christophe; Londei, Marco; McNamara, Peter; Nasoff, Marc; DiDonato, Michael; Glynne, Richard; Herman, Ann E.

Affiliation

Diaz-de-Durana Y; Genetics Department, Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America.

PLoS One ; 8(10): e78483, 2013.

Article in En | MEDLINE | ID: mdl-24205242

Subject(s)

Diabetes Mellitus, Type 1/immunology; Diabetes Mellitus, Type 1/therapy; Insulin-Secreting Cells/immunology; Interleukin-2/immunology; Animals; Diabetes Mellitus, Type 1/metabolism; Disease Models, Animal; Female; Glucagon/metabolism; Immunotherapy/methods; Insulin/metabolism; Insulin-Secreting Cells/metabolism; Interleukin-2/metabolism; Mice; Mice, Inbred NOD; Regeneration/immunology; T-Lymphocytes, Regulatory/immunology; T-Lymphocytes, Regulatory/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-2 / Diabetes Mellitus, Type 1 / Insulin-Secreting Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Type: Article Affiliation country: United States

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