Myelin alters the inflammatory phenotype of macrophages by activating PPARs.

Bogie, Jeroen F J; Jorissen, Winde; Mailleux, Jo; Nijland, Philip G; Zelcer, Noam; Vanmierlo, Tim; Van Horssen, Jack; Stinissen, Piet; Hellings, Niels; Hendriks, Jerome J A

Bogie, Jeroen F J; Jorissen, Winde; Mailleux, Jo; Nijland, Philip G; Zelcer, Noam; Vanmierlo, Tim; Van Horssen, Jack; Stinissen, Piet; Hellings, Niels; Hendriks, Jerome J A.

Affiliation

Bogie JF; Biomedical Research Institute, School of Life Sciences, Hasselt University / Transnational University Limburg, Diepenbeek, Belgium. Jerome.Hendriks@uhasselt.be.

Acta Neuropathol Commun ; 1: 43, 2013 Aug 02.

Article in En | MEDLINE | ID: mdl-24252308

Subject(s)

Macrophages/immunology; Multiple Sclerosis/immunology; Myelin Sheath/physiology; PPAR delta/metabolism; PPAR-beta/metabolism; Adult; Aged; Animals; Brain/immunology; Brain/pathology; Cell Proliferation/physiology; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental/immunology; Encephalomyelitis, Autoimmune, Experimental/pathology; Female; Humans; Lysosomes/metabolism; Male; Middle Aged; Multiple Sclerosis/pathology; Nitric Oxide/metabolism; Phosphatidylserines/administration & dosage; Phosphatidylserines/metabolism; Rats; Spleen/immunology; T-Lymphocytes/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: PPAR-beta / PPAR delta / Macrophages / Multiple Sclerosis / Myelin Sheath Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Acta Neuropathol Commun Year: 2013 Type: Article Affiliation country: Belgium

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