Subpopulations of myeloid-derived suppressor cells impair T cell responses through independent nitric oxide-related pathways.

Raber, Patrick L; Thevenot, Paul; Sierra, Rosa; Wyczechowska, Dorota; Halle, Daniel; Ramirez, Maria E; Ochoa, Augusto C; Fletcher, Matthew; Velasco, Cruz; Wilk, Anna; Reiss, Krzysztof; Rodriguez, Paulo C

Raber, Patrick L; Thevenot, Paul; Sierra, Rosa; Wyczechowska, Dorota; Halle, Daniel; Ramirez, Maria E; Ochoa, Augusto C; Fletcher, Matthew; Velasco, Cruz; Wilk, Anna; Reiss, Krzysztof; Rodriguez, Paulo C.

Affiliation

Raber PL; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA; Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA.

Int J Cancer ; 134(12): 2853-64, 2014 Jun 15.

Article in En | MEDLINE | ID: mdl-24259296

Subject(s)

CD8-Positive T-Lymphocytes/immunology; Granulocytes/immunology; Monocytes/immunology; Nitric Oxide/metabolism; Peroxynitrous Acid/metabolism; Animals; Cell Line, Tumor; Cell Proliferation; Female; Humans; Lymphocyte Activation/immunology; Membrane Glycoproteins/genetics; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidases/genetics; Neoplasms/immunology; Nitric Oxide Synthase Type II/genetics; Nitric Oxide Synthase Type III/biosynthesis; Nitric Oxide Synthase Type III/genetics; Nitrites/metabolism; Peroxynitrous Acid/biosynthesis; Reactive Oxygen Species/metabolism; Signal Transduction/immunology

Key words

MDSC; eNOS; peroxynitrites

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monocytes / CD8-Positive T-Lymphocytes / Peroxynitrous Acid / Granulocytes / Nitric Oxide Limits: Animals / Female / Humans Language: En Journal: Int J Cancer Year: 2014 Type: Article Affiliation country: LAOS

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