The Stream algorithm: computationally efficient ridge-regression via Bayesian model averaging, and applications to pharmacogenomic prediction of cancer cell line sensitivity.

Neto, Elias Chaibub; Jang, In Sock; Friend, Stephen H; Margolin, Adam A

Neto, Elias Chaibub; Jang, In Sock; Friend, Stephen H; Margolin, Adam A.

Affiliation

Neto EC; Sage Bionetworks, 1100 Fairview Avenue North, Seattle, Washington 98109, USA. elias.chaibub.neto@sagebase.org.

Pac Symp Biocomput ; : 27-38, 2014.

Article in En | MEDLINE | ID: mdl-24297531

Subject(s)

Algorithms; Pharmacogenetics/statistics & numerical data; Antineoplastic Agents/pharmacology; Artificial Intelligence; Bayes Theorem; Cell Line, Tumor; Computational Biology; Drug Resistance, Neoplasm/genetics; Humans; Neoplasms/drug therapy; Neoplasms/genetics; Regression Analysis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmacogenetics / Algorithms Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Pac Symp Biocomput Journal subject: BIOTECNOLOGIA / INFORMATICA MEDICA Year: 2014 Type: Article Affiliation country: United States

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