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Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection.
Link, John O; Taylor, James G; Xu, Lianhong; Mitchell, Michael; Guo, Hongyan; Liu, Hongtao; Kato, Darryl; Kirschberg, Thorsten; Sun, Jianyu; Squires, Neil; Parrish, Jay; Kellar, Terry; Yang, Zheng-Yu; Yang, Chris; Matles, Mike; Wang, Yujin; Wang, Kelly; Cheng, Guofeng; Tian, Yang; Mogalian, Erik; Mondou, Elsa; Cornpropst, Melanie; Perry, Jason; Desai, Manoj C.
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  • Link JO; Medicinal Chemistry, ‡Drug Metabolism, §Biology, ±Formulation and Process Development, ∥Clinical Research, and ⊥Structural Chemistry, Gilead Sciences , 333 Lakeside Drive, Foster City, California 94404, United States.
J Med Chem ; 57(5): 2033-46, 2014 03 13.
Article in En | MEDLINE | ID: mdl-24320933
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Benzimidazoles / Hepatitis C / Viral Nonstructural Proteins / Fluorenes Type of study: Clinical_trials Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2014 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Benzimidazoles / Hepatitis C / Viral Nonstructural Proteins / Fluorenes Type of study: Clinical_trials Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2014 Type: Article Affiliation country: United States