Pharmacokinetics of a new once-daily controlled-release sarpogrelate hydrochloride compared with immediate-release formulation and the effect of food.

Kim, T-E; Kim, J-R; Jung, J A; Kim, M-J; Lee, S-Y; Ko, J-W; Jung, W-T; Choi, Y-W; Lee, H J; Kim, S-H; Huh, W

Kim, T-E; Kim, J-R; Jung, J A; Kim, M-J; Lee, S-Y; Ko, J-W; Jung, W-T; Choi, Y-W; Lee, H J; Kim, S-H; Huh, W.

Affiliation

Kim TE; Department of Clinical Pharmacology, Konkuk University Medical Center, Seoul, Korea.

J Clin Pharm Ther ; 39(2): 192-5, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24325365

Subject(s)

Food-Drug Interactions; Platelet Aggregation Inhibitors/pharmacokinetics; Succinates/pharmacokinetics; Adult; Area Under Curve; Biological Availability; Chromatography, Liquid; Cross-Over Studies; Delayed-Action Preparations; Drug Administration Schedule; Half-Life; Humans; Male; Middle Aged; Models, Biological; Platelet Aggregation Inhibitors/administration & dosage; Succinates/administration & dosage; Tandem Mass Spectrometry; Young Adult

Key words

5-Hydroxytryptamine receptor subtype 2A (5HT2A); controlled release; food effect; pharmacokinetics; sarpogrelate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Succinates / Platelet Aggregation Inhibitors / Food-Drug Interactions Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans / Male / Middle aged Language: En Journal: J Clin Pharm Ther Journal subject: FARMACIA / TERAPEUTICA Year: 2014 Type: Article

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